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4-(4-Chlorophenethyl)piperazin-2-one → HCID 123402311、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-(4-Chlorophenethyl)piperazin-2-one | HCID 58092229 | — |
| 反応物 | tert-Butyl 8-bromo-6-methyl-3,4,5,6-tetrahydroazepino[4,3-b]indole-2(1H)-carboxylate | HCID 66874851 | — |
| 生成物 | HCID 123402311 | HCID 123402311 | 70.5% |
反応手順
tert-Butyl 8-bromo-6-methyl-3,4,5,6-tetrahydroazepino[4,3-b]indole-2(1H)-carboxylate (250 mg, 0.66 mmol) and 4-(4-chlorophenethyl)piperazin-2-one (157 mg, 0.66 mmol) were reacted following the procedure for Example 53 (step b) to provide the title compound (250 mg, 70%) as a colorless oil: ESI MS m/z 537 [M+H]+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08637501B2 |
| 出典データセット | uspto-grants-2014_01 |
| ORD ID | ord-98c3716962434ccbbce011c0356af47d |
| 出典メモ | uspto-grants-2014_01 |