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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 475005Generated: October 29, 2026

HCID 58092312, compound → HCID 58093418, compound

https://huagongshe.com/reaction/475005

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 58092312HCID 58092312—
Reactanttert-butyl 8-bromo-6-methyl-1,2,4,5-tetrahydroazepino[4,5-b]indole-3(6H)-carboxylateHCID 58093439—
ProductHCID 58093418HCID 5809341831.2%

Reaction Steps

4((3,5-Difluoropyridin-2-yl)methoxy)pyridin-2(1H)-one (100 mg, 0.418 mmol) and tert-butyl 8-bromo-6-methyl-1,2,4,5-tetrahydroazepino[4,5-b]indole-3(6H)-carboxylate (206 mg, 0.544 mmol) were reacted following the procedure for Example 2 (step d) to provide the title compound (70 mg, 30%) as a brown oil; ESI MS m/z 537 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08637501B2
Source datasetuspto-grants-2014_01
ORD IDord-0e9a1622d86e49b185b125d2e2b34356
Source noteuspto-grants-2014_01