Tetrahydrofuran → HCID 71272171, compound

Participants

Reaction Steps

To a solution of 1-(1-(tetrahydro-2H-pyran-2-yl)-1H-benzo[d]imidazol-5-yl)propan-1-one oxime (30 mg, 0.11 mmol) in THF (3 mL), Raney-Ni (50 mg) was added. The mixture was stirred at RT overnight. Removal of solvent followed by reverse-phase chromatography gave (4-ethyl-1-tetrahydropyran-2-yl-benzimidazol-5-yl)methanamine (10 mg, 35% yield) as a colorless oil.

Provenance & Evidence