HCID 86694693, compound → HCID 86694694, compound

Participants

Reaction Steps

To a solution of tert-butyl 4-ethyl-5-nitro-1H-benzo[d]imidazole-1-carboxylate (20.0 g, 0.07 mol) in dry MeOH (500 mL) was added Pd/C (1.5 g). The suspension was then stirred under hydrogen (3 kg pressure) for 6 h. After completion, the reaction mixture was filtered through a celite pad and concentrated to give tert-butyl 5-amino-4-ethyl-1H-benzo[d]imidazole-1-carboxylate (13.6 g, 76% yield). The crude product was used for the next step without further purification.

Provenance & Evidence