p-Toluenesulfonic acid monohydrate → HCID 178505864, compound

Participants

Reaction Steps

A mixture of 272 (140 mg, 0.31 mmol) and p-TsOH.H2O (59 mg, 0.31 mmol) in MeOH (5 mL) and H2O (1 mL) was heated at reflux for 2 h. The mixture was cooled and concentrated in vacuo. The crude product was purified by preparative HPLC to afford 50 mg (44%) of I-96 as white solid.

Provenance & Evidence