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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 47531Generated: October 25, 2026

Hydroxyacetone → 2-Propanone, 1-((methylsulfonyl)oxy)-

https://huagongshe.com/reaction/47531

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydroxyacetoneHCID 8299—
ReactantMethanesulfonyl chlorideHCID 31297—
ReactantSodium BicarbonateHCID 516892—
SolventChloroformHCID 6212—
Product2-Propanone, 1-((methylsulfonyl)oxy)-HCID 146754—

Reaction Steps

Thirty-seven (37) mg of hydroxyacetone was dissolved in 2 ml of chloroform, and to which 0.078 ml of methanesulfonyl chloride was added. After stirring the reaction liquid at room temperature for 30 minutes, saturated aqueous sodium bicarbonate solution was added and extracted with chloroform. The extract was dried over anhydrous sodium sulfate and concentrated to provide the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06699880B1
Source datasetuspto-grants-2004_03
ORD IDord-ae0dc196daec479296ba40aa26395f87
Source noteuspto-grants-2004_03