Carbamic acid, [1-(methoxymethyl)cyclopentyl]-, phenylmethyl ester → Cyclopentanamine, 1-(methoxymethyl)- (9CI)

Participants

Reaction Conditions

Reaction Steps

To a solution of (1-methoxymethyl-cyclopentyl)-carbamic acid benzyl ester (150 mg, 0.57 mmol) in MeOH (5 mL) was added HCO2NH4 (216 mg, 3.42 mmol), followed by Pd/C (10%, 6 mg, 0.057 mmol). The resulting mixture was heated, to 70° C., for 2 hours. The reaction mixture was filtered and concentrated to provide the titled compound. MS (DCI) m/e 130 (M+H)+.

Provenance & Evidence