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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 475559Generated: October 25, 2026

Ethyl bromopyruvate → Ethyl 2-(3,4-diethoxyphenyl)oxazole-4-carboxylate

https://huagongshe.com/reaction/475559

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl bromopyruvateHCID 66144—
Reactant3,4-DiethoxybenzamideHCID 340342—
ProductEthyl 2-(3,4-diethoxyphenyl)oxazole-4-carboxylateHCID 6898474985%

Reaction Steps

Using 10.4 g of 3,4-diethoxybenzamide and 19.5 g of ethyl 3-bromo-2-oxopropionate and following the procedure of Reference Example 5, 12.9 g of white powdery ethyl 2-(3,4-diethoxyphenyl)oxazole-4-carboxylate was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08637559B2
Source datasetuspto-grants-2014_01
ORD IDord-7433cedd04464a37bf7b10981f8d131f
Source noteuspto-grants-2014_01