Ethanone, 1-(2-chlorophenyl)- → HCID 57855807, compound

HRID 475587Notes

Reaction equation

HRID 475587 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8](=[O:10])[CH3:9].Cl[CH2:12][C:13]1[N:14]=[C:15]([C:18]2[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[C:20]([O:26][CH2:27][CH:28]3[CH2:30][CH2:29]3)[CH:19]=2)[O:16][CH:17]=1>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8](=[O:10])[CH2:9][CH2:12][C:13]1[N:14]=[C:15]([C:18]2[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[C:20]([O:26][CH2:27][CH:28]3[CH2:30][CH2:29]3)[CH:19]=2)[O:16][CH:17]=1

Participants

3

Reactant 2

HCID 72864Ethanone, 1-(2-chlorophenyl)-HCID 68982382HCID 68982382, compound

Product 1

HCID 57855807HCID 57855807, compoundYield 13.3%

Procedure

Using 0.31 g of 1-(2-chlorophenyl)ethanone and 0.59 g of 4-chloromethyl-2-(3-cyclopropylmethoxy-4-methoxyphenyl)oxazole obtained in Reference Example 11, 0.11 g of colorless oily 1-(2-chlorophenyl)-3-[2-(3-cyclopropylmethoxy-4-methoxyphenyl)oxazol-4-yl]propan-1-one was obtained in the same manner as in Example 177.

Workup

  1. customobtained in Reference Example 11

Sources & evidence

ORD record
ord-fae62f4215a943ef9a0bb2d2d2e5ba8b
Source dataset
uspto-grants-2014_01
Patent number
US08637559B2

Reaction notes

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