1-Bromo-2-methylpropane → HCID 86633757, compound

HRID 475603Notes

Reaction equation

HRID 475603 reaction equation
[F:1][CH2:2][CH2:3][O:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[C:11](=[O:28])[CH2:12][CH2:13][C:14]1[N:15]=[C:16]([C:19]2[CH:24]=[CH:23][C:22]([O:25][CH3:26])=[C:21]([OH:27])[CH:20]=2)[O:17][CH:18]=1.[CH2:29](Br)[CH:30]([CH3:32])[CH3:31]>>[F:1][CH2:2][CH2:3][O:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[C:11](=[O:28])[CH2:12][CH2:13][C:14]1[N:15]=[C:16]([C:19]2[CH:24]=[CH:23][C:22]([O:25][CH3:26])=[C:21]([O:27][CH2:29][CH:30]([CH3:32])[CH3:31])[CH:20]=2)[O:17][CH:18]=1

Participants

3

Reactant 2

HCID 65551-Bromo-2-methylpropaneHCID 86633756HCID 86633756, compound

Product 1

HCID 86633757HCID 86633757, compound

Procedure

Using the compound obtained in Example 271 and isobutyl bromide, white powdery 1-[2-(2-fluoroethoxy)phenyl]-3-[2-(3-isobutoxy-4-methoxyphenyl)oxazol-4-yl]propan-1-one was obtained following the procedure of Example 3.

Sources & evidence

ORD record
ord-f1822445ae664490a5bfc74ed7f96aa5
Source dataset
uspto-grants-2014_01
Patent number
US08637559B2

Reaction notes

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