Allyl bromide → HCID 57855712, compound

HRID 475615Notes

Reaction equation

[F:1][CH:2]([F:28])[O:3][C:4]1[CH:27]=[CH:26][CH:25]=[CH:24][C:5]=1[C:6]([NH:8][CH2:9][C:10]1[N:11]=[C:12]([C:15]2[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[C:17]([OH:23])[CH:16]=2)[O:13][CH:14]=1)=[O:7].[CH2:29](Br)[CH:30]=[CH2:31]>>[CH2:31]([O:23][C:17]1[CH:16]=[C:15]([C:12]2[O:13][CH:14]=[C:10]([CH2:9][NH:8][C:6](=[O:7])[C:5]3[CH:24]=[CH:25][CH:26]=[CH:27][C:4]=3[O:3][CH:2]([F:1])[F:28])[N:11]=2)[CH:20]=[CH:19][C:18]=1[O:21][CH3:22])[CH:30]=[CH2:29]

Participants

Reactant 2

HCID 7841Allyl bromide

HCID 57855721HCID 57855721, compound

Product 1

HCID 57855712HCID 57855712, compound

Procedure

Using the compound obtained in Example 321 and allyl bromide, white powdery N-[2-(3-allyloxy-4-methoxyphenyl)-oxazol-4-ylmethyl]-2-difluoromethoxybenzamide was obtained following the procedure of Example 3.

Sources & evidence

ORD record: ord-61bb64e403104ee19fa74f7d4ed4351d
Source dataset: uspto-grants-2014_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08637559B2

Reaction notes

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