Allyl bromide → HCID 68981444, compound

HRID 475651Notes

Reaction equation

[F:1][CH:2]([F:27])[O:3][C:4]1[CH:5]=[C:6]([C:11]2[O:12][CH:13]=[C:14]([CH2:16][NH:17][C:18](=[O:26])[C:19]3[C:24]([CH3:25])=[CH:23][CH:22]=[CH:21][N:20]=3)[N:15]=2)[CH:7]=[CH:8][C:9]=1[OH:10].[CH2:28](Br)[CH:29]=[CH2:30]>>[CH2:30]([O:10][C:9]1[CH:8]=[CH:7][C:6]([C:11]2[O:12][CH:13]=[C:14]([CH2:16][NH:17][C:18](=[O:26])[C:19]3[C:24]([CH3:25])=[CH:23][CH:22]=[CH:21][N:20]=3)[N:15]=2)=[CH:5][C:4]=1[O:3][CH:2]([F:1])[F:27])[CH:29]=[CH2:28]

Participants

Reactant 2

HCID 7841Allyl bromide

HCID 136356814HCID 136356814, compound

Product 1

HCID 68981444HCID 68981444, compound

Procedure

Using the compound obtained in Example 367 and allyl bromide, white powdery N-[2-(4-allyloxy-3-difluoromethoxy phenyl)oxazol-4-ylmethyl]-3-methylpicolinamide was obtained following the procedure of Example 98.

Sources & evidence

ORD record: ord-5599a768ef4d4091bf82fe54b9256037
Source dataset: uspto-grants-2014_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08637559B2

Reaction notes

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