1-Bromo-2-methylpropane → HCID 68986363, compound

HRID 475652Notes

Reaction equation

HRID 475652 reaction equation
[F:1][CH:2]([F:27])[O:3][C:4]1[CH:5]=[C:6]([C:11]2[O:12][CH:13]=[C:14]([CH2:16][NH:17][C:18](=[O:26])[C:19]3[C:24]([CH3:25])=[CH:23][CH:22]=[CH:21][N:20]=3)[N:15]=2)[CH:7]=[CH:8][C:9]=1[OH:10].[CH2:28](Br)[CH:29]([CH3:31])[CH3:30]>>[F:27][CH:2]([F:1])[O:3][C:4]1[CH:5]=[C:6]([C:11]2[O:12][CH:13]=[C:14]([CH2:16][NH:17][C:18](=[O:26])[C:19]3[C:24]([CH3:25])=[CH:23][CH:22]=[CH:21][N:20]=3)[N:15]=2)[CH:7]=[CH:8][C:9]=1[O:10][CH2:28][CH:29]([CH3:31])[CH3:30]

Participants

3

Reactant 2

HCID 65551-Bromo-2-methylpropaneHCID 136356814HCID 136356814, compound

Product 1

HCID 68986363HCID 68986363, compound

Procedure

Using the compound obtained in Example 367 and isobutyl bromide, white powdery N-[2-(3-difluoromethoxy-4-isobutoxy phenyl)oxazol-4-ylmethyl]-3-methylpicolinamide was obtained following the procedure of Example 98.

Sources & evidence

ORD record
ord-41630dc562dd4e21b2af5af171d67e66
Source dataset
uspto-grants-2014_01
Patent number
US08637559B2

Reaction notes

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