1,1,1-Trifluoro-2-iodoethane → HCID 57855773, compound

HRID 475657Notes

Reaction equation

HRID 475657 reaction equation
[F:1][CH:2]([F:29])[O:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]2[O:11][CH:12]=[C:13]([CH2:15][NH:16][C:17](=[O:27])[C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=3[O:24][CH2:25][CH3:26])[N:14]=2)=[CH:6][C:5]=1[OH:28].[F:30][C:31]([F:35])([F:34])[CH2:32]I>>[F:29][CH:2]([F:1])[O:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]2[O:11][CH:12]=[C:13]([CH2:15][NH:16][C:17](=[O:27])[C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=3[O:24][CH2:25][CH3:26])[N:14]=2)=[CH:6][C:5]=1[O:28][CH2:32][C:31]([F:35])([F:34])[F:30]

Participants

3

Reactant 2

HCID 677091,1,1-Trifluoro-2-iodoethaneHCID 68983382HCID 68983382, compound

Product 1

HCID 57855773HCID 57855773, compound

Procedure

Using the compound obtained in Example 347 and 1,1,1-trifluoro-2-iodoethane, white powdery N-{2-[4-difluoromethoxy-3-(2,2,2-trifluoroethoxy)phenyl]-oxazol-4-ylmethyl}-2-ethoxy benzamide was obtained following the procedure of Example 348.

Sources & evidence

ORD record
ord-d0cbcce6696345e781ad7d81a0ec4c9b
Source dataset
uspto-grants-2014_01
Patent number
US08637559B2

Reaction notes

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