HRID476135

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID10824

3-Methoxyaniline

C7H9NO

结构：CCOc1cc(OC2CC3C(=O)NC4(C(=O)O)CC4C=CCCCCN(C)C(=O)C3C2)c2ccc(OC)c(C)c2n1

HCID68694538

未命名化合物

PRODUCTS

生成物

结构：CCOc1cc(OC2CC3C(=O)NC4(C(=O)O)CC4C=CCCCCN(C)C(=O)C3C2)c2ccc(OC)cc2n1

HCID68692269

未命名化合物

PROCEDURE

实验过程

The title compound (4) was prepared from 3-methoxyaniline following the procedure (Steps A-J) reported for synthesis of 17-[2-ethoxy-7-methoxy-8-methylquinolin-4-yloxy]-13-methyl-2,14-dioxo-3,13-diazatricyclo[13.3.0.04,6]octadec-7-ene-4-carboxylic acid (2): m/z=552 (M+H)+.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-1657da74996d4c8fb1f29ec94c5368bf
来源数据集: uspto-grants-2014_01
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08637663B2
来源说明: uspto-grants-2014_01

反应 SMILES

COC1C=C(C=CC=1)N.[CH2:10]([O:12][C:13]1[CH:22]=[C:21]([O:23][CH:24]2[CH2:41][CH:40]3[CH:26]([C:27](=[O:47])[N:28]([CH3:46])[CH2:29][CH2:30][CH2:31][CH2:32][CH:33]=[CH:34][CH:35]4[C:37]([C:43]([OH:45])=[O:44])([NH:38][C:39]3=[O:42])[CH2:36]4)[CH2:25]2)[C:20]2[C:15](=[C:16](C)[C:17]([O:48][CH3:49])=[CH:18][CH:19]=2)[N:14]=1)[CH3:11]>>[CH2:10]([O:12][C:13]1[CH:22]=[C:21]([O:23][CH:24]2[CH2:41][CH:40]3[CH:26]([C:27](=[O:47])[N:28]([CH3:46])[CH2:29][CH2:30][CH2:31][CH2:32][CH:33]=[CH:34][CH:35]4[C:37]([C:43]([OH:45])=[O:44])([NH:38][C:39]3=[O:42])[CH2:36]4)[CH2:25]2)[C:20]2[C:15](=[CH:16][C:17]([O:48][CH3:49])=[CH:18][CH:19]=2)[N:14]=1)[CH3:11]