HRID476139

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11701043

2,3-dihydrobenzofuran-4-amine

C8H9NO

结构：CCOc1cc(OC2CC3C(=O)NC4(C(=O)O)CC4C=CCCCCN(C)C(=O)C3C2)c2ccc(OC)c(C)c2n1

HCID68694538

未命名化合物

PRODUCTS

生成物

结构：CCOc1cc(OC2CC3C(=O)NC4(C(=O)O)CC4C=CCCCCN(C)C(=O)C3C2)c2ccc3c(c2n1)CCO3

HCID68689921

未命名化合物

PROCEDURE

实验过程

The title compound (8) was prepared from 4-amino-2,3-dihydrobenzofurane following the procedure (Steps A-J) reported for synthesis of 17-[2-ethoxy-7-methoxy-8-methylquinolin-4-yloxy]-13-methyl-2,14-dioxo-3,13-diazatricyclo[13.3.0.046]-octadec-7-ene-4-carboxylic acid (2): m/z=564 (M+H)+.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-5a41f59bf9044ea292e8176850d175f0
来源数据集: uspto-grants-2014_01
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08637663B2
来源说明: uspto-grants-2014_01

反应 SMILES

NC1C2CCOC=2C=CC=1.[CH2:11]([O:13][C:14]1[CH:23]=[C:22]([O:24][CH:25]2[CH2:42][CH:41]3[CH:27]([C:28](=[O:48])[N:29]([CH3:47])[CH2:30][CH2:31][CH2:32][CH2:33][CH:34]=[CH:35][CH:36]4[C:38]([C:44]([OH:46])=[O:45])([NH:39][C:40]3=[O:43])[CH2:37]4)[CH2:26]2)[C:21]2[C:16](=[C:17]([CH3:51])[C:18]([O:49][CH3:50])=[CH:19][CH:20]=2)[N:15]=1)[CH3:12]>>[CH2:11]([O:13][C:14]1[CH:23]=[C:22]([O:24][CH:25]2[CH2:42][CH:41]3[CH:27]([C:28](=[O:48])[N:29]([CH3:47])[CH2:30][CH2:31][CH2:32][CH2:33][CH:34]=[CH:35][CH:36]4[C:38]([C:44]([OH:46])=[O:45])([NH:39][C:40]3=[O:43])[CH2:37]4)[CH2:26]2)[C:21]2[C:16](=[C:17]3[CH2:51][CH2:50][O:49][C:18]3=[CH:19][CH:20]=2)[N:15]=1)[CH3:12]