2-Hydrazinopyridine → HCID 136082873, compound

Participants

Reaction Conditions

Reaction Steps

2-hydrazinopyridine (62 mg, 0.57 mmol) was added to a solution of Compound 10 (113 mg, 0.520 mmol) synthesized in Step 1 of Example D in acetic acid (3 mL), followed by stirring under reflux at 120° C. for 30 minutes. The reaction solution was concentrated by distillation under reduced pressure, and ethyl acetate (5 mL) and water (5 mL) were added thereto, followed by extraction with ethyl acetate. The organic layer was dried over anhydrous sodium sulfate and then separated by column chromatography (n-Hex/EtOAc=3/1 (v/v)) to afford the title compound.

Provenance & Evidence