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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 476235Generated: October 25, 2026

2,4-Difluorophenylacetic acid → {(7R)-7-[[(2,4-difluorophenyl)acetyl] (methyl)amino]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl}acetic acid

https://huagongshe.com/reaction/476235

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-Difluorophenylacetic acidHCID 123581—
Reactantpropyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetateHCID 86655417—
Product{(7R)-7-[[(2,4-difluorophenyl)acetyl] (methyl)amino]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl}acetic acidHCID 54584673—

Reaction Steps

The title compound was prepared using analogous procedures described in Example 1 (Method A) from (2,4-difluorophenyl)acetic acid and propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate. MS (+ESI) m/z: 413.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08637671B2
Source datasetuspto-grants-2014_01
ORD IDord-ed5c64369e3b4be9be7fcc064cc057b1
Source noteuspto-grants-2014_01