1H-Indene-1-carboxylic acid, 2,3-dihydro- → HCID 54587620, compound

HRID 476240Notes

Reaction equation

HRID 476240 reaction equation
[CH:1]1([C:10]([OH:12])=O)[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH2:2]1.[CH3:13][NH:14][C@H:15]1[CH2:34][N:19]2[C:20]3[C:25]([C:26]([CH2:27][C:28]([O:30]CCC)=[O:29])=[C:18]2[CH2:17][CH2:16]1)=[CH:24][CH:23]=[CH:22][CH:21]=3>>[CH:1]1([C:10]([N:14]([CH3:13])[C@H:15]2[CH2:34][N:19]3[C:20]4[C:25]([C:26]([CH2:27][C:28]([OH:30])=[O:29])=[C:18]3[CH2:17][CH2:16]2)=[CH:24][CH:23]=[CH:22][CH:21]=4)=[O:12])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 857281H-Indene-1-carboxylic acid, 2,3-dihydro-HCID 86655417propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate

Product 1

HCID 54587620HCID 54587620, compound

Procedure

The title compound was prepared using analogous procedures described in Example 1 (Method A) from indane-1-carboxylic acid and propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate. MS (+ESI) m/z: 403.

Sources & evidence

ORD record
ord-6d1412ad00494a688cd51e01e67ca4ef
Source dataset
uspto-grants-2014_01
Patent number
US08637671B2

Reaction notes

Loading…