Cyclopropanecarboxylic acid → HCID 58349712, compound

HRID 476244Notes

Reaction equation

HRID 476244 reaction equation
[CH:1]1([C:4]([OH:6])=O)[CH2:3][CH2:2]1.[CH3:7][NH:8][C@H:9]1[CH2:28][N:13]2[C:14]3[C:19]([C:20]([CH2:21][C:22]([O:24]CCC)=[O:23])=[C:12]2[CH2:11][CH2:10]1)=[CH:18][CH:17]=[CH:16][CH:15]=3>>[CH:1]1([C:4]([N:8]([CH3:7])[C@H:9]2[CH2:28][N:13]3[C:14]4[C:19]([C:20]([CH2:21][C:22]([OH:24])=[O:23])=[C:12]3[CH2:11][CH2:10]2)=[CH:18][CH:17]=[CH:16][CH:15]=4)=[O:6])[CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 15655Cyclopropanecarboxylic acidHCID 86655417propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate

Product 1

HCID 58349712HCID 58349712, compound

Procedure

The title compound was prepared using analogous procedures described in Example 2 (Method B) from cyclopropanecarboxylic acid and propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate. MS (+ESI) m/z: 327.

Sources & evidence

ORD record
ord-f180c11c1fdd468199b6686afb38ed55
Source dataset
uspto-grants-2014_01
Patent number
US08637671B2

Reaction notes

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