4-Methoxyphenylacetyl chloride → HCID 54585608, compound

HRID 476247Notes

Reaction equation

HRID 476247 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][C:10](Cl)=[O:11])=[CH:5][CH:4]=1.[CH3:13][NH:14][C@H:15]1[CH2:34][N:19]2[C:20]3[C:25]([C:26]([CH2:27][C:28]([O:30]CCC)=[O:29])=[C:18]2[CH2:17][CH2:16]1)=[CH:24][CH:23]=[CH:22][CH:21]=3>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][C:10]([N:14]([CH3:13])[C@H:15]2[CH2:34][N:19]3[C:20]4[C:25]([C:26]([CH2:27][C:28]([OH:30])=[O:29])=[C:18]3[CH2:17][CH2:16]2)=[CH:24][CH:23]=[CH:22][CH:21]=4)=[O:11])=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 27346884-Methoxyphenylacetyl chlorideHCID 86655417propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate

Product 1

HCID 54585608HCID 54585608, compound

Procedure

The title compound was prepared using analogous procedures described in Example 2 (Method B) from (4-methoxyphenyl)acetyl chloride and propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate. MS (+ESI) m/z: 407.

Sources & evidence

ORD record
ord-ed678e4e667b4178b939362ede61dd12
Source dataset
uspto-grants-2014_01
Patent number
US08637671B2

Reaction notes

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