Phenylacetyl chloride → HCID 54582728, compound

HRID 476249Notes

Reaction equation

HRID 476249 reaction equation
[C:1]1([CH2:7][C:8](Cl)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:11][NH:12][C@H:13]1[CH2:32][N:17]2[C:18]3[C:23]([C:24]([CH2:25][C:26]([O:28]CCC)=[O:27])=[C:16]2[CH2:15][CH2:14]1)=[CH:22][CH:21]=[CH:20][CH:19]=3>>[CH3:11][N:12]([C:8](=[O:9])[CH2:7][C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)[C@H:13]1[CH2:32][N:17]2[C:18]3[C:23]([C:24]([CH2:25][C:26]([OH:28])=[O:27])=[C:16]2[CH2:15][CH2:14]1)=[CH:22][CH:21]=[CH:20][CH:19]=3

Participants

3

Reactant 2

HCID 7679Phenylacetyl chlorideHCID 86655417propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate

Product 1

HCID 54582728HCID 54582728, compound

Procedure

The title compound was prepared using analogous procedures described in Example 2 (Method B) from phenylacetyl chloride and propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate. MS (+ESI) m/z: 377.

Sources & evidence

ORD record
ord-81cd71973ab142f2be3d214839161bb6
Source dataset
uspto-grants-2014_01
Patent number
US08637671B2

Reaction notes

Loading…