3,4-Difluorophenylacetyl chloride → {(7R)-7-[[(3,4-difluorophenyl)acetyl](methyl)amino]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl}acetic acid

Participants

Role	Name	HCID	Charge
Reactant	3,4-Difluorophenylacetyl chloride	HCID 14618085	—
Reactant	propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate	HCID 86655417	—
Product	{(7R)-7-[[(3,4-difluorophenyl)acetyl](methyl)amino]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl}acetic acid	HCID 54580743	—

Reaction Steps

The title compound was prepared using analogous procedures described in Example 2 (Method B) from (3,4-difluorophenyl)acetyl chloride and propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate. MS (+ESI) m/z: 413.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08637671B2
Source dataset	uspto-grants-2014_01
ORD ID	ord-d06717925cc24f89be00b414a04d110e
Source note	uspto-grants-2014_01