HCID 16243950, compound → HCID 58349687, compound

HRID 476258Notes

Reaction equation

HRID 476258 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([N:12]2[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]2)[C:9]([OH:11])=O)=[CH:4][CH:3]=1.[CH3:18][NH:19][C@H:20]1[CH2:39][N:24]2[C:25]3[C:30]([C:31]([CH2:32][C:33]([O:35]CCC)=[O:34])=[C:23]2[CH2:22][CH2:21]1)=[CH:29][CH:28]=[CH:27][CH:26]=3>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([CH:8]([N:12]2[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]2)[C:9]([N:19]([CH3:18])[C@H:20]2[CH2:39][N:24]3[C:25]4[C:30]([C:31]([CH2:32][C:33]([OH:35])=[O:34])=[C:23]3[CH2:22][CH2:21]2)=[CH:29][CH:28]=[CH:27][CH:26]=4)=[O:11])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 16243950HCID 16243950, compoundHCID 86655417propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate

Product 1

HCID 58349687HCID 58349687, compound

Procedure

The title compound was prepared using analogous procedures described in Example 1 (Method A) from (4-fluorophenyl)(piperidin-1-yl)acetic acid and propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate. MS (+ESI) m/z: 478.

Sources & evidence

ORD record
ord-21fa618884784711b3d841200f2851da
Source dataset
uspto-grants-2014_01
Patent number
US08637671B2

Reaction notes

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