3-Thiophenacetic acid → HCID 58349713, compound

HRID 476263Notes

Reaction equation

HRID 476263 reaction equation
[S:1]1[CH:5]=[CH:4][C:3]([CH2:6][C:7]([OH:9])=O)=[CH:2]1.[CH3:10][NH:11][C@H:12]1[CH2:31][N:16]2[C:17]3[C:22]([C:23]([CH2:24][C:25]([O:27]CCC)=[O:26])=[C:15]2[CH2:14][CH2:13]1)=[CH:21][CH:20]=[CH:19][CH:18]=3>>[CH3:10][N:11]([C:7](=[O:9])[CH2:6][C:3]1[CH:4]=[CH:5][S:1][CH:2]=1)[C@H:12]1[CH2:31][N:16]2[C:17]3[C:22]([C:23]([CH2:24][C:25]([OH:27])=[O:26])=[C:15]2[CH2:14][CH2:13]1)=[CH:21][CH:20]=[CH:19][CH:18]=3

Participants

3

Reactant 2

HCID 234043-Thiophenacetic acidHCID 86655417propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate

Product 1

HCID 58349713HCID 58349713, compound

Procedure

The title compound was prepared using analogous procedures described in Example 1 (Method A) from thiophen-3-yl acetic acid and propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate. MS (+ESI) m/z: 383.

Sources & evidence

ORD record
ord-a14243d41822497084177c3b2cb3011b
Source dataset
uspto-grants-2014_01
Patent number
US08637671B2

Reaction notes

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