2-Phenylbutyryl chloride → HCID 67310782, compound

HRID 476266Notes

Reaction equation

HRID 476266 reaction equation
[C:1]1([CH:7]([CH2:11][CH3:12])[C:8](Cl)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:13][NH:14][C@H:15]1[CH2:34][N:19]2[C:20]3[C:25]([C:26]([CH2:27][C:28]([O:30]CCC)=[O:29])=[C:18]2[CH2:17][CH2:16]1)=[CH:24][CH:23]=[CH:22][CH:21]=3>>[C:1]1([CH:7]([C:11]2[CH:12]=[CH:3][CH:2]=[CH:1][CH:6]=2)[C:8]([N:14]([CH3:13])[C@H:15]2[CH2:34][N:19]3[C:20]4[C:25]([C:26]([CH2:27][C:28]([OH:30])=[O:29])=[C:18]3[CH2:17][CH2:16]2)=[CH:24][CH:23]=[CH:22][CH:21]=4)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 981732-Phenylbutyryl chlorideHCID 86655417propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate

Product 1

HCID 67310782HCID 67310782, compound

Procedure

The title compound was prepared using analogous procedures described in Example 2 (Method B) from 2-phenylbutanoyl chloride and propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate. MS (+ESI) m/z: 405.

Sources & evidence

ORD record
ord-2b23bbd4325c41b9ad3c347a08689911
Source dataset
uspto-grants-2014_01
Patent number
US08637671B2

Reaction notes

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