HCID 67304381, compound → HCID 58349675, compound

HRID 476270Notes

Reaction equation

HRID 476270 reaction equation
[CH:1]1([CH2:4][CH:5]([C:9]2[CH:14]=[CH:13][C:12]([F:15])=[CH:11][CH:10]=2)[C:6]([OH:8])=O)[CH2:3][CH2:2]1.[CH3:16][NH:17][C@H:18]1[CH2:37][N:22]2[C:23]3[C:28]([C:29]([CH2:30][C:31]([O:33]CCC)=[O:32])=[C:21]2[CH2:20][CH2:19]1)=[CH:27][CH:26]=[CH:25][CH:24]=3>>[CH:1]1([CH2:4][CH:5]([C:9]2[CH:14]=[CH:13][C:12]([F:15])=[CH:11][CH:10]=2)[C:6]([N:17]([CH3:16])[C@H:18]2[CH2:37][N:22]3[C:23]4[C:28]([C:29]([CH2:30][C:31]([OH:33])=[O:32])=[C:21]3[CH2:20][CH2:19]2)=[CH:27][CH:26]=[CH:25][CH:24]=4)=[O:8])[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 67304381HCID 67304381, compoundHCID 86655417propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate

Product 1

HCID 58349675HCID 58349675, compound

Procedure

The title compound was prepared using analogous procedures described in Example 1 (Method A) from 3-cyclopropyl-2-(4-fluorophenyl)propanoic acid and propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate. MS (+ESI) m/z: 449.

Sources & evidence

ORD record
ord-76d8c7d912ba47648f31606ac20a0d7d
Source dataset
uspto-grants-2014_01
Patent number
US08637671B2

Reaction notes

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