HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-Atrolactic acid → [(7R)-7-{[(2S)-2-hydroxy-2-phenylpropanoyl](methyl)amino}-6,7,8,9-tetrahydropyrido[1,2-a]-indol-10-yl]acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-Atrolactic acid | HCID 445144 | — |
| Reactant | propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate | HCID 86655417 | — |
| Product | [(7R)-7-{[(2S)-2-hydroxy-2-phenylpropanoyl](methyl)amino}-6,7,8,9-tetrahydropyrido[1,2-a]-indol-10-yl]acetic acid | HCID 58349676 | — |
Reaction Steps
The title compound was prepared using analogous procedures described in Example 1 (Method A) from (2S)-2-hydroxy-2-phenylpropanoic acid and propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate. MS (+ES I) m/z: 407.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08637671B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-95b8217abaca40ff8e540f68c84cce1f |
| Source note | uspto-grants-2014_01 |