Imidazo(1,2-a)pyridine-3-acetic acid → HCID 58349684, compound

HRID 476276Notes

Reaction equation

HRID 476276 reaction equation
[N:1]1[CH:2]=[C:3]([CH2:10][C:11]([OH:13])=O)[N:4]2[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=12.[CH3:14][NH:15][C@H:16]1[CH2:35][N:20]2[C:21]3[C:26]([C:27]([CH2:28][C:29]([O:31]CCC)=[O:30])=[C:19]2[CH2:18][CH2:17]1)=[CH:25][CH:24]=[CH:23][CH:22]=3>>[N:1]1[CH:2]=[C:3]([CH2:10][C:11]([N:15]([CH3:14])[C@H:16]2[CH2:35][N:20]3[C:21]4[C:26]([C:27]([CH2:28][C:29]([OH:31])=[O:30])=[C:19]3[CH2:18][CH2:17]2)=[CH:25][CH:24]=[CH:23][CH:22]=4)=[O:13])[N:4]2[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=12

Participants

3

Reactant 2

HCID 87284Imidazo(1,2-a)pyridine-3-acetic acidHCID 86655417propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate

Product 1

HCID 58349684HCID 58349684, compound

Procedure

The title compound was prepared using analogous procedures described in Example 1 (Method A) from imidazo[1,2-a]pyridin-3-ylacetic acid and propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate. MS (+ESI) m/z: 417.

Sources & evidence

ORD record
ord-465ea5bcd5e34bfab4c8ae14b055f007
Source dataset
uspto-grants-2014_01
Patent number
US08637671B2

Reaction notes

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