2-(4-Fluorophenyl)acetic acid → HCID 58349690, compound

HRID 476277Notes

Reaction equation

HRID 476277 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]([OH:11])=O)=[CH:4][CH:3]=1.[CH3:12][NH:13][C@@H:14]1[CH2:31][N:18]2[C:19]3[C:24]([C:25]([CH2:26][C:27]([O:29]C)=[O:28])=[C:17]2[CH2:16][CH2:15]1)=[CH:23][CH:22]=[CH:21][CH:20]=3>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:8][C:9]([N:13]([CH3:12])[C@@H:14]2[CH2:31][N:18]3[C:19]4[C:24]([C:25]([CH2:26][C:27]([OH:29])=[O:28])=[C:17]3[CH2:16][CH2:15]2)=[CH:23][CH:22]=[CH:21][CH:20]=4)=[O:11])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 98372-(4-Fluorophenyl)acetic acidHCID 86655420HCID 86655420, compound

Product 1

HCID 58349690HCID 58349690, compound

Procedure

The title compound was prepared using analogous procedures described in Example 1 (Method A) from (4-fluorophenyl)acetic acid and methyl [(7S)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate. MS (+ESI) m/z: 395.

Sources & evidence

ORD record
ord-8bf5fd124b4f41de8c2e92666028a423
Source dataset
uspto-grants-2014_01
Patent number
US08637671B2

Reaction notes

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