4-(4-Fluorophenyl)oxane-4-carboxylic acid → (R)-2-(7-(4-(4-fluorophenyl)-N-methyltetrahydro-2H-pyran-4-carboxamido)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl)acetic acid

Participants

Role	Name	HCID	Charge
Reactant	4-(4-Fluorophenyl)oxane-4-carboxylic acid	HCID 6484229	—
Reactant	propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate	HCID 86655417	—
Product	(R)-2-(7-(4-(4-fluorophenyl)-N-methyltetrahydro-2H-pyran-4-carboxamido)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl)acetic acid	HCID 54582729	—

Reaction Steps

The title compound was prepared using analogous procedures described in Example 1 (Method A) from 4-(4-fluorophenyl)tetrahydro-2H-pyran-4-carboxylic acid and propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate. MS (+ESI) m/z: 465.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08637671B2
Source dataset	uspto-grants-2014_01
ORD ID	ord-606be5f51fae48c0b48c032d2727c0e9
Source note	uspto-grants-2014_01