Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl acetoacetate → HCID 178463089, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl acetoacetate | HCID 7757 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Hydrazine, ethyl-, ethanedioate (1:1) | HCID 96181 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | HCID 178463089 | HCID 178463089 | — |
반응 단계
A suspension of 23 g of ethyl hydrazine oxalate and 22 ml of triethylamine in 500 ml of toluene was stirred at room temperature for 15 minutes. 17 ml of methyl acetoacetate was added and the mixture was azeotroped for 1.5 hours. The mixture was evaporated and the residue was purified by flash chromatography on silica gel using dichloromethane/methanol (97:3) for the elution to give 19 g of 2-ethyl-5-methyl-2H-pyrazol-3-ol as an orange solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06699887B2 |
| 출처 데이터셋 | uspto-grants-2004_03 |
| ORD ID | ord-3e722a6946a544cca7bd5c0d21f6cef4 |
| 출처 메모 | uspto-grants-2004_03 |