1,2,3,4-Tetrahydro-1-naphthoic acid → HCID 54580742, compound

HRID 476280Notes

Reaction equation

HRID 476280 reaction equation
[CH:1]1([C:11]([OH:13])=O)[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][CH2:2]1.[CH3:14][NH:15][C@H:16]1[CH2:35][N:20]2[C:21]3[C:26]([C:27]([CH2:28][C:29]([O:31]CCC)=[O:30])=[C:19]2[CH2:18][CH2:17]1)=[CH:25][CH:24]=[CH:23][CH:22]=3>>[CH3:14][N:15]([C:11]([CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][CH2:2]1)=[O:13])[C@H:16]1[CH2:35][N:20]2[C:21]3[C:26]([C:27]([CH2:28][C:29]([OH:31])=[O:30])=[C:19]2[CH2:18][CH2:17]1)=[CH:25][CH:24]=[CH:23][CH:22]=3

Participants

3

Reactant 2

HCID 125981461,2,3,4-Tetrahydro-1-naphthoic acidHCID 86655417propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate

Product 1

HCID 54580742HCID 54580742, compound

Procedure

The title compound was prepared using analogous procedures described in Example 1 (Method A) from 1,2,3,4-tetrahydronaphthalene-1-carboxylic acid and propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate. MS (+ESI) m/z: 417.

Sources & evidence

ORD record
ord-7dd5f23390db43268bae9ac24effdf3a
Source dataset
uspto-grants-2014_01
Patent number
US08637671B2

Reaction notes

Loading…