2-(pyridin-2-yl)propanoic acid → HCID 58349680, compound

HRID 476284Notes

Reaction equation

HRID 476284 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH:7]([CH3:11])[C:8]([OH:10])=O.[CH3:12][NH:13][C@H:14]1[CH2:33][N:18]2[C:19]3[C:24]([C:25]([CH2:26][C:27]([O:29]CCC)=[O:28])=[C:17]2[CH2:16][CH2:15]1)=[CH:23][CH:22]=[CH:21][CH:20]=3>>[CH3:12][N:13]([C:8](=[O:10])[CH:7]([C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][N:1]=1)[CH3:11])[C@H:14]1[CH2:33][N:18]2[C:19]3[C:24]([C:25]([CH2:26][C:27]([OH:29])=[O:28])=[C:17]2[CH2:16][CH2:15]1)=[CH:23][CH:22]=[CH:21][CH:20]=3

Participants

3

Reactant 2

HCID 190757882-(pyridin-2-yl)propanoic acidHCID 86655417propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate

Product 1

HCID 58349680HCID 58349680, compound

Procedure

The title compound was prepared using analogous procedures described in Example 1 (Method A) from 2-(pyridin-2-yl)propanoic acid and propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate. MS (+ESI) m/z: 392.

Sources & evidence

ORD record
ord-55c8793bc56c4a558d9b660158f827cb
Source dataset
uspto-grants-2014_01
Patent number
US08637671B2

Reaction notes

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