反应详情

To an ice-cooled solution of 3,4,5-trifluoroaniline (2.00 g; 13.6 mmol) in 50% tetrafluoroboric acid (5.0 ml) was added dropwise, with stirring, a solution of sodium nitrite (1.04 g; 15.1 mmol) in water (1.5 ml). After a further 15 minutes at 0° C., the precipitated solid was filtered off and washed with cold diethyl ether. After drying under reduced pressure, 2.91 g (11.8 mmol; 87% of theory) of the title compound were obtained in the form of a colorless powder.

1. additionwas added dropwise
2. filtrationthe precipitated solid was filtered off
3. washwashed with cold diethyl ether
4. dry with materialAfter drying under reduced pressure, 2.91 g (11.8 mmol; 87% of theory) of the title compound
5. customwere obtained in the form of a colorless powder