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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 476463Generated: October 30, 2026

3-Bromoquinoline → 3,5-Dimethyl-4-quinolin-3-yl-1,2-oxazole

https://huagongshe.com/reaction/476463

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-BromoquinolineHCID 21413—
Reactant3,5-Dimethylisoxazole-4-boronic acid pinacol esterHCID 2758656—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
CatalystHCID 178439014HCID 178439014—
SolventWaterHCID 962—
SolventTetrahydrofuranHCID 8028—
Product3,5-Dimethyl-4-quinolin-3-yl-1,2-oxazoleHCID 4424355441.4%
WorkupAcetoneHCID 180—
Internal standardNaphthaleneHCID 931—
WorkupWaterHCID 962—

Reaction Conditions

Temperature110 °C

Provenance & Evidence

DOI10.1039/C6RE00153J
Source datasetReizman Suzuki Cross-Coupling
ORD IDord-a967767fd35a4a12b12dfafc0dcdf0cb
Source noteReizman Suzuki Cross-Coupling