HCID 131715457, compound → HCID 131715456, compound

HRID 4765Notes

Reaction equation

HRID 4765 reaction equation

[ClH:1].C[C:3]1[CH:19]=[C:18]([OH:20])[CH:17]=[C:16]([CH3:21])[C:4]=1[CH2:5][C@@H:6]([C:8]([NH:10][C@@H:11]([C:13]([OH:15])=O)[CH3:12])=[O:9])[NH2:7]>CO>[ClH:1].[CH3:21][C:16]1[CH:17]=[C:18]([OH:20])[CH:19]=[CH:3][C:4]=1[CH2:5][C@@H:6]([C:8]([NH:10][C@@H:11]([C:13]([NH:10][CH2:8][CH2:6][CH2:5][C:4]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:3]=1)=[O:15])[CH3:12])=[O:9])[NH2:7]

Participants

3

Reactant 1

HCID 131715457HCID 131715457, compound

Product 1

HCID 131715456HCID 131715456, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The title compound was prepared by the method of Example 4 from diastereomer F of the title compound of Example 11, Route B. [α]D -23.8 (MeOH)

Sources & evidence

ORD record: ord-1397e52558304bc794ebf0497ed5c6b3
Source dataset: uspto-grants-1988_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04727189

Reaction notes

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