HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 476506Generated: October 30, 2026
3-Bromoquinoline → 3,5-Dimethyl-4-quinolin-3-yl-1,2-oxazole
https://huagongshe.com/reaction/476506
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Bromoquinoline | HCID 21413 | — |
| Reactant | 3,5-Dimethylisoxazole-4-boronic acid pinacol ester | HCID 2758656 | — |
| Reagent | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Catalyst | HCID 178458461 | HCID 178458461 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3,5-Dimethyl-4-quinolin-3-yl-1,2-oxazole | HCID 44243554 | 5.6% |
| Workup | Acetone | HCID 180 | — |
| Internal standard | Naphthalene | HCID 931 | — |
| Workup | Water | HCID 962 | — |
Reaction Conditions
| Temperature | 65.30000305175781 °C |
|---|
Provenance & Evidence
| DOI | 10.1039/C6RE00153J |
|---|
| Source dataset | Reizman Suzuki Cross-Coupling |
|---|
| ORD ID | ord-d4a24963ecb8480281d0715281aef514 |
|---|
| Source note | Reizman Suzuki Cross-Coupling |
|---|
