HRID476546

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID1030

1,2-Propylene glycol

C3H8O2

HCID81848

2-Pyrrolidinone, 1-[3-(dimethylamino)propyl]-

C9H18N2O

结构：CCCCCCCCCCCCCCCCCCOS(=O)(=O)c1ccc(C)cc1

HCID229551

Octadecyl p-Toluenesulfonate

C25H44O3S

PRODUCTS

生成物

结构：CCCCCCCCCCCCCCCCCC[N+](C)(C)CCCN1CCCC1=O.Cc1ccc(S(=O)(=O)[O-])cc1

HCID86743541

未命名化合物

CONDITIONS

反应条件

温度: 100 °C

PROCEDURE

实验过程

To a 100 ml round bottom flask equipped with a thermometer and stirrer containing 167 g. of propylene glycol was added 50.7 g. of octadecyl-p-toluenesulfonate and 20.9 g. of [(dimethylamino)propyl]-2-pyrrolidone. The mixture was heated to 100° C. and stirred at that temperature for 6 hours after which it was cooled and recovered. Analysis by quaternary tetraphenyl boron indicated 22% activity corresponding to a 74% conversion.

WORKUP

后处理

customTo a 100 ml round bottom flask equipped with a thermometer and stirrer
additioncontaining 167 g
temperaturewas cooled
customrecovered

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-8387e17c5ae8486dbaf3b26e0530a509
来源数据集: uspto-grants-1989_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04885158
来源说明: uspto-grants-1989_12

反应 SMILES

C(O)C(O)C.[CH2:6]([O:24][S:25]([C:28]1[CH:33]=[CH:32][C:31]([CH3:34])=[CH:30][CH:29]=1)(=[O:27])=[O:26])[CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23].[CH3:35][N:36]([CH2:38][CH2:39][CH2:40][N:41]1[CH2:45][CH2:44][CH2:43][C:42]1=[O:46])[CH3:37]>>[S:25]([C:28]1[CH:33]=[CH:32][C:31]([CH3:34])=[CH:30][CH:29]=1)([O-:27])(=[O:26])=[O:24].[CH2:6]([N+:36]([CH3:35])([CH3:37])[CH2:38][CH2:39][CH2:40][N:41]1[CH2:45][CH2:44][CH2:43][C:42]1=[O:46])[CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23]