Ammonium Chloride → HCID 86743542, compound

Participants

Reaction Steps

For example, when sodium (or potassium) ethylmercaptide was used in place of the sodium methylmercaptide in Step A, one obtained (2S,3R,4R)-5-(ethylthio)-3-hydroxy-4-methyl-2-(methylamino)-pentanoic acid. Likewise, when the methylamine hydrochloride of Step H was replaced by ammonium chloride, (2S,3R,4S)-2-amino-3-hydroxy- 4-methyl-5-(methylthio)-pentanoic acid was obtained, and when ethylamine hydrochloride was used, (2A,3R,4S)-2-(ethylamino)-3-hydroxy-4-methyl-5-(methylthio) pentanoic acid was obatined.

Provenance & Evidence