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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 47657Generated: October 26, 2026

(4-Methoxyphenyl)boronic acid → 4-(4'-Methoxy-biphenyl-3-yl)-5-methyl-2-(4-trifluoromethyl-phenyl)-oxazole

https://huagongshe.com/reaction/47657

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Methoxyphenyl)boronic acidHCID 201262—
Reactant2-[4-(Trifluoromethyl)phenyl]-4-(4-bromophenyl)-5-methyloxazoleHCID 10691278—
Product4-(4'-Methoxy-biphenyl-3-yl)-5-methyl-2-(4-trifluoromethyl-phenyl)-oxazoleHCID 9931322—

Reaction Steps

The title compound was prepared from 4-(4-bromo-phenyl)-5-methyl-2-(4-trifluoromethyl-phenyl)-oxazole, and 4-methoxy-benzeneboronic acid in substantially the same manner, as described in Example 1 step c, and was obtained as a white solid, mp 93-94° C.; MS m/e 409 (M+);

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06699896B1
Source datasetuspto-grants-2004_03
ORD IDord-2dd43d3ec2b44a48900afbe6dea479ec
Source noteuspto-grants-2004_03