反应详情

A mixture of 4,5-diamino-2-(2-propoxyphenyl)pyrimidin-6-one (0.3 g), formamidine acetate (0.18 g) and anhydrous sodium acetate (0.1 g) was heated in an oil bath at 155°-165° C. for 21/2 hours. The mixture melted and then resolidified. Ethanol (1 ml) was added and the title compound was collected by filtration, 0.31 g, m.p. 256°-258° C.

1. temperaturewas heated in an oil bath at 155°-165° C. for 21/2 hours
2. filtrationthe title compound was collected by filtration, 0.31 g, m.p. 256°-258° C.