Sulfanilamide → HCID 131716204, compound

HRID 476601Notes

Reaction equation

HRID 476601 reaction equation
[S:1]([NH2:11])(=[O:10])([C:3]1[CH:8]=[CH:7][C:6]([NH2:9])=[CH:5][CH:4]=1)=[O:2].O[CH:13]=[C:14]1[C:23](=[S:24])[C:22]2[C:17](=[CH:18][CH:19]=[C:20]([CH3:25])[CH:21]=2)[O:16][CH:15]1[C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1>C(O)C>[S:1]([C:3]1[CH:4]=[CH:5][C:6]([NH:9][CH:13]=[C:14]2[C:23](=[S:24])[C:22]3[C:17](=[CH:18][CH:19]=[C:20]([CH3:25])[CH:21]=3)[O:16][CH:15]2[C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)=[CH:7][CH:8]=1)(=[O:10])(=[O:2])[NH2:11]

Participants

4

Reactant 2

HCID 5333SulfanilamideHCID 178422546HCID 178422546, compound

Product 1

HCID 131716204HCID 131716204, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a refluxing solution of 13 g sulfanilamide in 800 ml absolute ethanol is added 21 g 3-hydroxymethylidene-6-methyl-thioflavanone. After sixteen hours the reaction mixture is cooled and the crystals which separated are collected. After recrystallisation in a mixture of acetone and light petroleums, pure 3-(N-4-sulfamoylphenyl)aminomethylidene-6-methyl-thioflavanone is obtained as yellow crystals; m.p. 210°-213° C.

Workup

  1. temperatureAfter sixteen hours the reaction mixture is cooled
  2. customthe crystals which separated
  3. customare collected
  4. customAfter recrystallisation
  5. additionin a mixture of acetone and light petroleums

Sources & evidence

ORD record
ord-fd18d00659cd436882808c6416dff100
Source dataset
uspto-grants-1989_12
Patent number
US04885298

Reaction notes

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