Veratryl chloride → HCID 14499767, compound

Participants

Reaction Steps

A mixture of 4.76 g (20 mmol) of 2-[(4-pyridyl)-carbonyl]-1,2,3,4-tetrahydroisoquinoline, 4.5 g (24 mmol) of 3,4-dimethoxybenzyl chloride and 200 ml of ethyl acetate is heated under reflux for 20 h. The mixture obtained is allowed to cool, and the precipitate is separated off by filtration and washed with ether. 6.6 g of salt are collected, this being used without further purification in the following stage.

Provenance & Evidence