2-Nitropropane → HCID 178443682, compound

HRID 476669Notes

Reaction equation

HRID 476669 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH3:9].[N+:10]([CH:13]([CH3:15])[CH3:14])([O-:12])=[O:11]>CO>[N+:10]([C-:13]([CH3:15])[CH3:14])([O-:12])=[O:11].[CH2:2]([NH3+:1])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH3:9]

Participants

4

Reactant 2

HCID 3982-NitropropaneHCID 8143Octylamine

Product 1

HCID 178443682HCID 178443682, compoundYield 97.7%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Conditions

Temperature
40 °C

Procedure

Into a flask, 129 g (1.0 mole) of 1-aminooctane and 100 ml of methanol were charged, and then 89 g (1.0 mole) of 2-nitropropane were dropped into the flask maintained at about 40° C over a period of about 30 minutes. After that, upon maintaining the mixture at the same temperature for 30 minutes, crystals were precipitated to give slurry. The reaction mixture was cooled to a temperature of 5° C and then filtered. The filtered precipitates were washed with 30 ml of cold methanol and dried under reduced pressure to obtain 213 g of 1-octylammonium 2-nitropropan-2-ide with a yield of 97.7%.

Workup

  1. temperatureAfter that, upon maintaining the mixture at the same temperature for 30 minutes
  2. customcrystals were precipitated
  3. customto give slurry
  4. temperatureThe reaction mixture was cooled to a temperature of 5° C
  5. filtrationfiltered
  6. customThe filtered precipitates
  7. washwere washed with 30 ml of cold methanol
  8. customdried under reduced pressure

Sources & evidence

ORD record
ord-bf97e0130cd04d4bbd64bdc556306da7
Source dataset
uspto-grants-1989_12
Patent number
US04885322

Reaction notes

Loading…