Triethylamine → Butanamide, 4-chloro-N-(2,3,5,6,7,8-hexahydronaphtho[2,3-b]furan-7-yl)-

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Reaction Steps

4.2 g of 4-chlorobutyryl chloride are added at room temperature to a mixture of 5 g of the compound of Example 2 and 4.2 g of triethylamine in 60 ml of benzene. After 1 hour at room temperature, the medium is diluted with water and filtered and the aqueous phase is extracted with benzene. The filtrate and the precipitate are combined and the benzene is evaporated off under vacuum. The dry residue is solidified in ether.

Provenance & Evidence