HuagongsheHuagongshe Chemistry Print Report · For research reference only
(5-Aminopentyl)diethylamine → P,P-bis(2,2-dimethyl-1-aziridinyl)-N-(5-diethylamino-1-pentyl)-phosphinic amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (5-Aminopentyl)diethylamine | HCID 4584949 | — |
| Reactant | P,P-bis(2,2-dimethyl-1-aziridinyl)phosphinyl chloride | HCID 13511140 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | P,P-bis(2,2-dimethyl-1-aziridinyl)-N-(5-diethylamino-1-pentyl)-phosphinic amide | HCID 19836605 | 90% |
Reaction Steps
In a similar manner 0.025 moles of P,P-bis(2,2-dimethyl-1-aziridinyl)phosphinoyl chloride in about 170 mL of THF are treated by dropwise addition with 0.026 moles of 5-diethylaminopentylamine in 25 mL of THF, stirred for several hours at ambient temperature, filtered, concentrated by rotary evaporation and vacuum distilled to yield about 90% pure P,P-bis(2,2-dimethyl-1-aziridinyl)-N-(5-diethylamino-1-pentyl)-phosphinic amide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04886790 |
| Source dataset | uspto-grants-1989_12 |
| ORD ID | ord-9aef35d6daf64598af0ba4a421975c18 |
| Source note | uspto-grants-1989_12 |