Potassium Iodide → HCID 14698767, compound

Participants

Reaction Steps

This compound was prepared according to the procedure of Example 1. A mixture of 4.6 g (0.015 mole) of α,α-bis-(p-fluorophenyl)-4-piperidinemethanol, 2.7 g (0.015 mole) of 6-(2-chloroethyl)tetrahydro-3-methyl-2H-1,3-oxazin-2-one, 5.3 g (0.05 mole) of anhydrous sodium carbonate and 0.4 g of potassium iodide in 100 ml of 1-butanol gave a glass as residue. The glass was converted to the oxalate and the solid was recrystallized from absolute ethanol to yield 4.9 g (61%) of white solid, m.p. 193°-194° C., with decomposition.

Provenance & Evidence