Hydrochloric Acid → HCID 14698757, compound

Participants

Reaction Steps

This compound was prepared according to the procedure of Example 1. A mixture of 4.5 g (0.015 mole) of α,α-bis-(p-fluorophenyl)-4-piperidinemethanol, 3.5 g (0.015 mole) of 5-(2-chloroethyl)-3-phenyl-2-oxazolidinone, 5.3 g (0.05 mole) of anhydrous sodium carbonate and 0.4 g of potassium iodide in 100 ml of 1-butanol gave a brown gloss as residue. The glass was converted to the hydrochloride and the solid was recrystallized from 95% ethanol to yield 6.3 g (79%) of white solid, m.p. 180°-183° C. with decomposition.

Provenance & Evidence