Oxalic Acid → HCID 19836712, compound

HRID 476945Notes

Reaction equation

HRID 476945 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([C:16]2[CH:21]=[CH:20][C:19]([F:22])=[CH:18][CH:17]=2)([CH:10]2[CH2:15][CH2:14][NH:13][CH2:12][CH2:11]2)[OH:9])=[CH:4][CH:3]=1.Cl[CH2:24][CH2:25][CH2:26][CH:27]1[CH2:31][O:30][C:29](=[O:32])[N:28]1[CH3:33].[C:34]([OH:39])(=[O:38])[C:35]([OH:37])=[O:36]>>[C:34]([OH:39])(=[O:38])[C:35]([OH:37])=[O:36].[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([C:16]2[CH:17]=[CH:18][C:19]([F:22])=[CH:20][CH:21]=2)([OH:9])[CH:10]2[CH2:11][CH2:12][N:13]([CH2:24][CH2:25][CH2:26][CH:27]3[CH2:31][O:30][C:29](=[O:32])[N:28]3[CH3:33])[CH2:14][CH2:15]2)=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 971Oxalic AcidHCID 11208889Bis(4-fluorophenyl)(piperidin-4-yl)methanolHCID 54539155HCID 54539155, compound

Product 1

HCID 19836712HCID 19836712, compound

Procedure

Following the procedure of Example 1, α,α-bis(p-fluorophenyl)-4-piperidinemethanol and 4-[(3-chloro)propyl]-3-methyl-2-oxazolidinone are reacted and the product thereof is reacted with oxalic acid to give the title compound.

Workup

  1. customare reacted

Sources & evidence

ORD record
ord-90a65c9d3f8f4197ba78efb77c7cdeb1
Source dataset
uspto-grants-1989_12
Patent number
US04886794

Reaction notes

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